Ixabiso leMveliso yoThengiso lweCholine Chloride CAS 67-48-1

Intshayelelo

I-Choline chloride yikhompawundi ye-organic. Yikhompawundi yetyuwa ene-ion ze-chloride kunye nee-cation ze-choline.

I-Choline chloride yinto eqinileyo engenambala, enyibilikayo emanzini. Inencasa enamandla ye-ammonium chloride. I-Choline chloride ineempawu zokujiya kwaye ingasetyenziswa njenge-hemostatic agent. Ikwasetyenziswa njenge-reagent yokufunda inkqubo ye-cholinergic kunye ne-neurology.

Kwizinto eziphilayo, i-choline yi-neurotransmitter ebalulekileyo ebandakanyeka kwiinkqubo ezininzi ze-physiological, kubandakanya i-neurotransmission, inkumbulo, kunye nokuhamba kwemisipha. I-choline chloride idlala indima ebalulekileyo kunyango nakwi-biochemistry.

Ipropati ye-physicochemical

I-Choline chloride yinto eqinileyo engenambala ekristale. Ineempawu zomzimba nezekhemikhali ezilandelayo:

3. Ukunyibilika: I-Choline chloride inokunyibilika kakuhle emanzini kwaye inokunyibilika emanzini ukuze yenze isisombululo.

4. Uzinzo: I-Choline chloride yikhompawundi ezinzileyo ekulula ukuyibolisa okanye ukuyibola.

5. I-asidi kunye ne-alkali: I-Choline chloride yikhompawundi ye-alkaline, enokuthi iphendule kunye ne-asidi ivelise iityuwa ezifanayo.

6. I-Hygroscopicity: I-Choline chloride inovelwano ngakumbi kumswakama kwaye ine-hygroscopicity ethile.

7. Ukutsha: I-Choline chloride iyatsha, kodwa iya kukhupha iigesi ezinobuthi xa itshisiwe.

Indlela yokulungiselela

I-Choline chloride ingalungiswa ngeendlela ezilandelayo:

Indlela eqhelekileyo yokulungiselela kukusabela kwe-choline kunye ne-hydrogen chloride. I-Choline iphendulwa ngesisombululo se-sodium hydroxide ukwenza ityuwa ye-choline. Emva koko, ityuwa ye-choline iyanyibilika emanzini kwaye kongezwa isixa esaneleyo segesi ye-hydrogen chloride. Ukusabela kwenzeka iiyure ezininzi phantsi kweemeko zokuxutywa nokufudumeza. Iikristale ze-choline chloride zifunyenwe ngokuhluzwa kunye nokukristala.

Enye indlela yokulungisa i-choline chloride kukusebenzisa i-reaction ye-choline phosphate kunye ne-sulfoxide chloride. Nyibilikisa i-choline phosphate kwi-methylene chloride. Emva koko, i-sulfoxide chloride yongezwa kancinci kwaye i-reaction ithatha iiyure ezininzi. Emva kokuba i-reaction igqityiwe, iikristale ze-choline chloride zifunyanwa ngokuphola kunye ne-crystallization.

Kwezi ndlela zimbini zingasentla, iikristale ze-choline chloride ezifunyenweyo kufuneka ziphathwe kakuhle, zomiswe kwaye zicocwe ukuze kufunyanwe iimveliso ze-choline chloride ezicocekileyo kakhulu.

Imo yokugcina

I-Choline chloride yikhompawundi ecaphukisayo nerhabaxa efuna amanyathelo athile okhuseleko xa igcinwa. Nantsi indlela egcinwa ngayo i-choline chloride:
1. Izikhongozeli zokugcina: Izinto ezinokumelana nokugqwala okunamandla mazikhethwe, ezifana nezikhongozeli ze-polyethylene okanye zeglasi. Izikhongozeli mazivalwe kakuhle ukuze kuthintelwe ukungena komswakama nomoya.

2. Indawo yokugcina: Ukuvezwa kwe-choline chloride emoyeni kufuneka kuthintelwe ukuthintela ukufunxwa komswakama. Indawo yokugcina kufuneka igcinwe yomile, ipholile kwaye ingabikho elangeni ngqo.

4. Kuphephe ukukhanya: i-choline chloride kulula ukuyitshabalalisa ekukhanyeni, kwaye kufuneka kuthintelwe ukukhanya kwelanga okanye eminye imithombo yokukhanya enamandla kangangoko kunokwenzeka.

5. Ukuchonga ilebheli: Kwisikhongozeli sokugcina, igama lekhemikhali, uhlobo oluyingozi, umhla wokugcina kunye nolunye ulwazi kufuneka luphawulwe ngokucacileyo ukuze kube lula ukuchongwa nokulawulwa.

6. Amanyathelo okhuseleko: Nxiba iiglavu zokuzikhusela ezifanelekileyo, iiglasi zokukhusela kunye nempahla yokukhusela xa ugcina kwaye uphatha i-choline chloride. Kuphephe ukudibana ngqo nolusu, ukuphefumla igesi, okanye indlela yokugaya ukutya.
Xa ugcina, qiniseka ukuba ulandela iinkqubo zokusebenza zokhuseleko kunye nemithetho nemigaqo.

Umsebenzi kunye nokusetyenziswa

I-Choline chloride yikhemikhali esetyenziswa kwikhemikhali.

I-Choline chloride sisongezelelo esibalulekileyo sesondlo esisetyenziswa kakhulu kwifomyula yeentsana kunye neemveliso zempilo. Inceda iiseli zikhule kwaye zisebenze kakuhle, igcina umsebenzi wenkqubo yemithambo-luvo, kwaye ibalulekile ekuphuhliseni umsebenzi wobuchopho kunye nenkumbulo.

Okwesibini, i-choline chloride ikwasetyenziswa kwicandelo lezonyango. Ingasetyenziselwa ukunyanga ukungabikho kwe-choline, ukukhuthaza ukwenziwa kunye nokukhululwa kwe-choline, kunye nokuphucula iimpawu. I-choline chloride ikwasetyenziswa njengesiqalisi kwaye inokudlala indima kunyango lokukhubazeka kwemisipha.

I-B vitamin choline yinxalenye ebalulekileyo yemizimba yabantu neyezilwanyana, edla ngokubizwa ngokuba ziivithamini ze-B okanye i-vitamin B4, yi-molecule encinci ye-organic efunekayo ekugcineni imisebenzi yomzimba emzimbeni wesilwanyana, izilwanyana zinokwenziwa, kodwa zihlala zifuna ukongezwa ekutyeni, yenye yeevithamini ezisetyenziswa kakhulu. Ingalawula imetabolism kunye nokuguqulwa kwamafutha kwizilwanyana, ithintele ukubekwa kwamafutha kunye nokonakala kwezicubu kwisibindi nakwizintso, ikhuthaze ukwakheka kwee-amino acid, iphucule izinga lokusetyenziswa kwee-amino acid, kwaye igcine inxalenye ye-methionine. I-Choline chloride okwangoku yeyona ndlela isetyenziswa kakhulu kwaye inoqoqosho ye-choline, yimveliso yevithamini enyibilikayo emanzini, yinxalenye ye-acetylcholine, i-ovophosphate kunye ne-neurophosphate kwizicubu zebhayoloji, inokusindisa i-methionine. Yinto ebalulekileyo efunekayo kwimfuyo, iinkukhu kunye neentlanzi, inokulawula imetabolism kunye nokuguqulwa kwamafutha emzimbeni wesilwanyana, inokuthintela ukubekwa kwesibindi kunye nokonakala kwezicubu zaso njengomnikeli we-methyl, inokukhuthaza ukwakheka kwee-amino acid, iphucule ukusetyenziswa kwee-amino acid. Isetyenziswa kakhulu ekuxubeni izongezo kwisondlo sezilwanyana. Kwinkqubo yokusetyenziswa, ukongeza ekuthinteleni ukufunxwa komswakama wayo, kufuneka kuqatshelwe ukuba zonke izondlo zongezwe i-choline chloride njengenkqubo yokugqibela, kuba inefuthe elibi kwezinye iivithamini, ngakumbi xa kukho izinto zesinyithi, ukutshatyalaliswa kweevithamini A, D, K kuyakhawuleza, ngoko ke i-choline akufuneki yongezwe kumalungiselelo amaninzi. Ukusetyenziswa kwemihla ngemihla, ukutya okongeziweyo okudityanisiweyo kufuneka kusetyenziswe ngokukhawuleza. Uvavanyo lubonisa ukuba i-choline chloride ibaluleke kakhulu kwiinkukhu nakwiinkukhu. Ii-amino acids kunye ne-lecithin ezenziwe yiyo zithuthwa ziye kuzo zonke iindawo zomzimba wenkukhu, ezinokuthintela ukuqokelelwa kwamafutha kwisibindi nakwizintso, zikhawulezise ukukhula kweenkukhu kwaye ziphucule izinga lokuveliswa kwamaqanda kunye nezinga lokuqandusela. Iipropati I-Acicular white crystalline powder. Ivumba elincinci lentlanzi, incasa ekrakra enetyuwa, ukufunxwa komswakama okulula, ukungaguquguquki kwi-lye. Indlela yokusebenza I-Choline chloride (CC) yi-homologue yeChemicalbook kwaye inezinye izinto ezifanayo kodwa ikwanomahluko amaninzi. I-hormone ayiguquguquki lula zizityalo, kodwa i-choline chloride ingasetyenziswa ngokukhawuleza zizityalo. Emva kokuba ifunxwe ziziqu, amagqabi kunye neengcambu ngexesha lokukhula kwezityalo, i-choline chloride idluliselwa ngokukhawuleza kwindawo esebenzayo, enokukhuthaza i-photosynthesis yamagqabi, ithintele ukuphefumla okuncinci kwezityalo ze-C3, ikhuthaze uphuhliso lweengcambu, kwaye ivumele i-photosynthesis ukuba ithuthwe iye kwiingcambu ezingaphantsi komhlaba kunye neengcambu kangangoko kunokwenzeka, ngaloo ndlela inyusa kakhulu isivuno kwaye iphucule umgangatho weengcambu kunye neengcambu. Inokuphucula imisebenzi eyahlukeneyo yomzimba yezityalo, inokuphucula izinga lokuhluma kwembewu yezityalo, ikhuthaze ukuhluma kweengcambu, yakhe izithole ezomeleleyo, inyuse isivuno, iphucule umgangatho wezityalo. Inokunyusa ukwakheka kunye nomlinganiselo we-phosphatidylcholine kwi-membrane ye-plasma, ngaloo ndlela ichaphazela isakhiwo kunye nokuzinza kwe-membrane, inciphise ukuvuza kwe-ion, kwaye yongeze izinto ezahlukeneyo ze-anti-lipid oxidation kunye nee-agents zokususa ii-radicals ze-oxygen free, ii-anions ze-superoxide kunye ne-hydroxyl free radicals eziyingozi kwiiseli zezityalo, ezidlala indima ebalulekileyo ekuchaseni izityalo kubushushu obuphantsi, ukukhanya okuphantsi, imbalela kunye nezinye iingcinezelo.

Sebenzisa

I-Choline chloride ingasetyenziswa njengesongezelelo sesondlo. I-Choline chloride luhlobo lomkhuthazi we-photosynthesis yezityalo, olunefuthe elicacileyo ekwandiseni isivuno, kwaye lunokusetyenziselwa ukwandisa isivuno sombona, umoba, iitapile ezimnandi, iitapile, iradish, itswele, umqhaphu, icuba, imifuno, iidiliya, imango, njl. Kunyango lwesibindi esinamafutha kunye ne-cirrhosis. Ikwasetyenziswa njengesongezelelo sokondla imfuyo, inokukhuthaza i-ovary ukuba ivelise amaqanda amaninzi, inkunkuma kunye nemfuyo, iintlanzi kunye nokunye ukutyeba. I-choline chloride yi-hydrochloride ye-choline, sisongezelelo sesondlo esisebenzayo kakhulu kunye nearhente yokususa amafutha. Ikhuthaza imetabolism yamafutha kwaye ithintela ukuqokelelwa kwamafutha esibindini. Njengemveliso yeevithamini, isetyenziswa kakhulu kumayeza, iimveliso zokhathalelo lwempilo kunye nokongezwa kokutya. Njengesongezelelo sokondla, i-choline chloride ithandwa ngabasebenzisi basekhaya ngenxa yomxholo wayo ophezulu we-choline (85%) kunye nexabiso eliphantsi.