Silinganise amanqanaba omchamo we-3-phenoxybenzoic acid (3-PBA), i-pyrethroid metabolite, kwi-1239 yasemaphandleni nabasezidolophini abadala baseKorea. Siphinde sahlola i-pyrethroid exposure usebenzisa umthombo wedatha yemibuzo;
Isibulali-zinambuzane sasekhayaizitshizi zingowona mthombo uphambili wokuvezwa kwinqanaba loluntu kwi-pyrethroids phakathi kwabantu abadala abadala eMzantsi Korea, isilumkiso ngesidingo solawulo olukhulu lwezinto ezisingqongileyo apho iipyrethroids zihlala zivezwa khona, kubandakanywa izitshizi ze-pesticide.
Ngezi zizathu, ukufunda iziphumo ze-pyrethroids kubantu abadala kunokubaluleka eKorea nakwamanye amazwe anabemi abakhula ngokukhawuleza. Nangona kunjalo, kukho inani elilinganiselweyo lezifundo ezithelekisa ukuvezwa kwe-pyrethroid okanye amanqanaba e-3-PBA kubantu abadala abadala emaphandleni okanye kwimimandla yasezidolophini, kwaye izifundo ezimbalwa zichaza iindlela ezinokubakho zokuvezwa kunye nemithombo enokubakho yokuvezwa.
Ke ngoko, silinganise amanqanaba e-3-PBA kwiisampulu zomchamo zabantu abadala eKorea kwaye sithelekisa ukugxininiswa kwe-3-PBA kumchamo wabantu abadala basemaphandleni nasezidolophini. Ukongeza, siye savavanya umyinge ongaphezulu kwemida yangoku ukumisela ukuvezwa kwepyrethroid phakathi kwabantu abadala eKorea. Siphinde savavanya imithombo enokubakho yokuvezwa kwepyrethroid sisebenzisa imibuzo kwaye siyinxibelelanisa namanqanaba omchamo we-3-PBA.
Kolu phononongo, silinganise amanqanaba e-3-PBA e-urinary kubantu abadala baseKorea abahlala emaphandleni nasezidolophini kwaye bavavanya ubudlelwane phakathi kwemithombo enokubakho ye-pyrethroid exposure kunye ne-urinary 3-PBA amanqanaba. Siphinde sagqiba umlinganiselo wokugqithiswa kwemida ekhoyo kwaye sivavanye ukungafani phakathi kunye ne-intra-individual kumanqanaba e-3-PBA.
Kuphononongo olupapashwe ngaphambili, sifumene ulungelelwaniso olubalulekileyo phakathi kwamanqanaba omchamo we-3-PBA kunye nokwehla kokusebenza kwemiphunga kubantu abadala basezidolophini eMzantsi Korea [3]. Ngenxa yokuba sifumene ukuba abantu abadala basezidolophini baseKorea baye bavezwa kumanqanaba aphezulu e-pyrethroids kuphononongo lwethu lwangaphambili [3], sithe gqolo sithelekisa amanqanaba e-3-PBA e-urinary ye-3-PBA yabantu abadala basemaphandleni nabasezidolophini ukuvavanya ubungakanani bexabiso le-pyrethroids elingaphezulu. Olu phononongo emva koko lwavavanya imithombo enokubakho yokuvezwa kwepyrethroids.
Isifundo sethu sinamandla amaninzi. Sisebenzise imilinganiselo ephindaphindiweyo yomchamo we-3-PBA ukubonisa ukubonakaliswa kwe-pyrethroid. Olu luyilo lwephaneli yobude bunokubonisa utshintsho lwexeshana kwi-pyrethroid exposure, enokutshintsha ngokulula ekuhambeni kwexesha. Ukongezelela, ngolu qulunqo lwesifundo, sinokuhlola isifundo ngasinye njengolawulo lwakhe kwaye sivavanye iziphumo zexesha elifutshane le-pyrethroid exposure usebenzisa i-3-PBA njenge-covariate yekhosi yexesha ngaphakathi kwabantu. Ukongeza, saba ngabokuqala ukuchonga imithombo yokusingqongileyo (engeyiyo eyomsebenzi) yokuvezwa kwepyrethroid kubantu abadala abadala eKorea. Noko ke, ufundisiso lwethu lukwanazo nemida. Kule sifundo, siqokelele ulwazi malunga nokusetyenziswa kwe-insecticidal sprays usebenzisa i-questionnaire, ngoko ke ixesha eliphakathi kokusetyenziswa kwe-insecticidal sprays kunye nokuqokelela umchamo alikwazanga ukumiselwa. Nangona iipatheni zokuziphatha zokusetyenziswa kwesitshizi sokubulala izinambuzane zingatshintshwa lula, ngenxa yemetabolism ekhawulezileyo yepyrethroids emzimbeni womntu, ixesha lekhefu phakathi kokusetyenziswa kwesitshizi sokubulala izinambuzane kunye nokuqokelelwa komchamo kunokuchaphazela kakhulu ukugxilwa komchamo kwe-3-PBA. Ukongezelela, abathathi-nxaxheba bethu abazange bamele njengoko sigxininise kwindawo enye kuphela yasemaphandleni kunye neyodolophini, nangona amanqanaba ethu e-3-PBA afaniswa nalawo alinganiswe ngabantu abadala, kubandakanywa nabantu abadala, kwi-KoNEHS. Ke ngoko, eminye imithombo yokusingqongileyo ehambelana nokuvezwa kwepyrethroid kufuneka ifundwe ngakumbi kubameli babantu abadala.
Ke, abantu abadala eKorea bavezwe kuxinzelelo oluphezulu lwepyrethroids, kunye nokusetyenziswa kwezitshizi zokubulala izinambuzane ngowona mthombo uphambili wokuvezwa kwendalo. Ngaloo ndlela, uphando olongezelelweyo luyafuneka kwimithombo ye-pyrethroid exposure phakathi kwabantu abadala abadala eKorea, kunye nolawulo olungqongqo kwizinto ezihlala zibonakaliswe ngokusingqongileyo, kubandakanywa nokusetyenziswa kwezitshizi ze-insecticide, ziyafuneka ukukhusela abantu abathintekayo kwi-pyrethroids, kubandakanywa ukuvezwa kweekhemikhali zokusingqongileyo. abantu abadala.
Ixesha lokuposa: Sep-27-2024