Uphando olutsha oluvela kwiYunivesithi yase-Iowa lubonisa ukuba abantu abanamanqanaba aphezulu ekhemikhali ethile emizimbeni yabo, nto leyo ebonisa ukuba bachatshazelwa zizibulali-zinambuzane ezisetyenziswa rhoqo, banamathuba amaninzi okufa ngenxa yesifo sentliziyo.
Iziphumo, ezipapashwe kwi-JAMA Internal Medicine, zibonisa ukuba abantu abachaphazeleka kakhulu zizibulali-zinambuzane ze-pyrethroid banamathuba angaphantsi kathathu okufa ngenxa yesifo sentliziyo kunabantu abachaphazeleka kancinci okanye abangenazo kwaphela izibulali-zinambuzane ze-pyrethroid.
Iziphumo zivela kuhlalutyo lwesampulu yabantu abadala baseMelika emele ilizwe lonke, kungekuphela nje abo basebenza kwezolimo, utshilo uWei Bao, uprofesa oncedisayo we-epidemiology kwiSikolo sezeMpilo yoLuntu kwiYunivesithi yase-Iowa kunye nombhali wolu phononongo. Oku kuthetha ukuba iziphumo zinefuthe kwimpilo yoluntu kuluntu ngokubanzi.
Ukwalumkisile ukuba ngenxa yokuba olu luphononongo lokujonga, alunakukwazi ukumisela ukuba abantu abakwisampulu bafe ngenxa yokuchatshazelwa ngqo yi-pyrethroids. Iziphumo zibonisa ukuba kunokwenzeka ukuba kubekho unxibelelwano, kodwa uphando olungakumbi luyadingeka ukuphinda iziphumo nokufumanisa indlela esebenza ngayo i-biological, utshilo.
Iipyrethroids ziphakathi kwezona zinambuzane zisetyenziswa kakhulu ngokwemarike, zibala uninzi lwezinambuzane zorhwebo zasekhaya. Zifumaneka kwiintlobo ezininzi zorhwebo zezinambuzane kwaye zisetyenziswa kakhulu ekulawuleni izinambuzane kwiindawo zezolimo, zikawonke-wonke nakwiindawo zokuhlala. Iimetabolites zepyrethroids, ezifana ne-3-phenoxybenzoic acid, zinokufumaneka kumchamo wabantu abachaphazeleka yipyrethroids.
UBao kunye neqela lakhe lophando bahlalutye idatha ngamanqanaba e-3-phenoxybenzoic acid kwiisampuli zomchamo ezivela kubantu abadala abayi-2,116 abaneminyaka engama-20 nangaphezulu abathathe inxaxheba kwiNational Health and Nutrition Examination Survey phakathi kowama-1999 nowama-2002. Baqokelele idatha yokufa ukuze babone ukuba bangaphi abantu abadala kwisampulu yabo yedatha abasweleke ngo-2015 kwaye kutheni.
Bafumanise ukuba kwixesha eliphakathi lokulandelela eliyiminyaka eli-14, ngo-2015, abantu abanamanqanaba aphezulu e-3-phenoxybenzoic acid kwiisampuli zomchamo babenamathuba angama-56 ekhulwini okufa ngenxa yesizathu kunabantu abanamanqanaba aphantsi okuvezwa. Isifo sentliziyo, esiyeyona nto iphambili yokufa, sinamathuba aphindwe kathathu.
Nangona uphando lukaBao lungakhange lumisele indlela abantu abachaphazeleka ngayo yi-pyrethroids, uthe uphando lwangaphambili lubonise ukuba uninzi lochaphazeleko lwe-pyrethroid lwenzeka ngokutya, njengoko abantu abatya iziqhamo nemifuno efafazwe nge-pyrethroids besitya le khemikhali. Ukusetyenziswa kwe-pyrethroids ukulawula izinambuzane egadini nasemakhaya nako kungumthombo obalulekileyo wokosuleleka. Ii-pyrethroids zikwakho eluthulini lwasekhaya apho kusetyenziswa khona ezi zinambuzane.
UBao waphawula ukuba isabelo semarikeizibulali-zinambuzane ze-pyrethroidliye landa ukususela kwixesha lophando luka-1999-2002, nto leyo eyenza ukuba kube nokwenzeka ukuba ukufa kwentliziyo okunxulumene nokuchaphazeleka kwazo kunyuke. Nangona kunjalo, uphando olongezelelekileyo luyafuneka ukuvavanya ukuba le ngcamango ichanekile na, utshilo uBao.
Eli phepha, elithi “Umbutho wokuvezwa kwizinambuzane ezibulala izinambuzane ze-pyrethroid kunye nomngcipheko wokufa okubangelwa zizo zonke izizathu kunye nezizathu ezithile phakathi kwabantu abadala base-US,” labhalwa ngokubambisana nguBuyun Liu kunye noHans-Joachim Lemler beSikolo sezeMpilo yoLuntu seYunivesithi yase-Illinois. , kunye noDerek Simonson, umfundi ophumelele kwiYunivesithi yase-Illinois kwi-human toxicology. Lapapashwa kwi-JAMA Internal Medicine yomhla wama-30 kuDisemba, ngo-2019.
Ixesha leposi: Matshi-15-2024