I-Thiostrepton ethengiswa ngexabiso eliphantsi ekumgangatho ophezulu 99% CAS No 1393-48-2

Intshayelelo

I-THIOSTREPTON yi-antibiotic enamandla ephuma kwimveliso yokubilisa yeentlobo ezithile zebhaktiriya ye-Actinomycete. Ikwiklasi ye-thiopeptide yamayeza okubulala iintsholongwane kwaye ifumene udumo ngokusebenza kwayo okumangalisayo ngokuchasene neebhaktiriya ezahlukeneyo ze-Gram-positive, kubandakanya i-MRSA (i-methicillin-resistant Staphylococcus aureus).IThiostreptonifundwe kakhulu kwaye ibonise ithemba kwiindlela ezahlukeneyo zonyango, lwezilwanyana, kunye nezolimo. Ngeempawu zayo ezikhethekileyo kunye neempawu ezibalaseleyo zokulwa neentsholongwane, iThiostrepton iyaqhubeka nokuguqula icandelo lonyango lwee-antibiotic.

Iimbonakalo

1. Amandla:IThiostreptonIyaziwa ngamandla ayo akhethekileyo okulwa neentsholongwane ezininzi eziyingozi kunye neefungi. Isebenza ngokuthintela ngokukhetha ukwenziwa kweeproteni zebhaktheriya, iqinisekisa isenzo esijoliswe kuzo nxamnye neentsholongwane ezibangela izifo ngelixa igcina iintsholongwane eziluncedo.

2. I-Broad Spectrum: I-spectrum ye-Thiostrepton ibandakanya iintsholongwane ezininzi ze-Gram-positive kunye nezinye iintlobo ze-anaerobic. Oku kuguquguquka kuvumela uluhlu olubanzi lwezicelo kwiindawo ezahlukeneyo zonyango, zezilwanyana, kunye nezolimo.

3. Ukhuseleko: I-Thiostrepton ineprofayili yokhuseleko egqwesileyo, nto leyo eyenza ukuba ifaneleke ukusetyenziswa kwiintlobo ngeentlobo zezilwanyana. Ityhefu yayo ephantsi kunye neziphumo zayo ezingathandekiyo zivumela ukusetyenziswa kwayo kwiindawo ezinobuzaza, ezifana neeyunithi ze-ICU kunye neefama zezilwanyana.

4. Ukuthintela Ukuxhathisa: Ngokungafaniyo nezinye ii-antibiotics, iThiostrepton ibonakalise ukuthambekela okuphantsi kokukhula kokuxhathisa iintsholongwane ngenxa yendlela yayo yokusebenza eyahlukileyo. Oku kuyenza ibe sisixhobo esibalulekileyo ekulweni nomba okhulayo wokuxhathisa ii-antibiotics.

Isicelo

1. Ukhathalelo lwempilo yabantu: I-Thiostrepton ibonakalise amandla amakhulu kwizicelo zempilo yabantu. Isetyenziswa kakhulu ekunyangeni izifo zolusu ezifana ne-impetigo, i-dermatitis, kunye ne-cellulitis ebangelwa yi-Staphylococcus aureus kunye ne-Streptococcus pyogenes. Ngaphezu koko, i-Thiostrepton ibonise iziphumo ezithembisayo kunyango lwezifo zomchamo, kubandakanya i-pneumonia kunye ne-bronchitis. Ukusebenza kwayo nxamnye ne-MRSA, uhlobo oludumileyo olumelana namayeza okubulala iintsholongwane, kuye kwayenza yaba luncedo kakhulu kwiindawo zesibhedlele.

2. Unyango lwezilwanyana: I-Thiostrepton ikwasetyenziswa kakhulu kunyango lwezilwanyana. Ijongana neentlobo ngeentlobo zezifo ezibangelwa ziintsholongwane ezichaphazela imfuyo, iinkukhu, kunye nezilwanyana ezihamba nazo. Ukusebenza kwayo ngokuchasene nezifo eziqhelekileyo ezifana ne-Staphylococcus, i-Streptococcus, kunye ne-Clostridium species kube negalelo elikhulu ekuphuculeni impilo yezilwanyana kunye nokuphila kakuhle. Ngaphezu koko, iprofayili yokhuseleko egqwesileyo ye-Thiostrepton iyenza ibe lukhetho olufanelekileyo lokunyanga izifo kwizilwanyana, inciphisa iziphumo ebezingalindelekanga.

3. Ezolimo: I-Thiostrepton inamandla amakhulu ekusetyenzisweni kwezolimo. Ingalwa neentsholongwane zezityalo ezifana ne-Actinomyces kunye ne-Streptomyces, inciphise ukwanda kwezifo zezityalo kwaye iphucule isivuno. I-Thiostrepton ingasetyenziswa njenge-spray yamagqabi okanye kunyango lwembewu ukubonelela ngokhuseleko kwizifo zefungus kunye neebhaktiriya kwizityalo ezahlukeneyo. Ngokulawula izifo zezityalo ngokufanelekileyo, i-Thiostrepton inegalelo kwezolimo ezizinzileyo kunye nokhuseleko lokutya.

Ukusetyenziswa

Ukusetyenziswa okuphambili kweThiostrepton kukwinyango nasekuthinteleni usulelo lweentsholongwane. Ithintela ukwenziwa kweeproteni kwiintsholongwane, ngaloo ndlela ithintela ukukhula nokwanda kwazo. Oku kuyenza ibe sisixhobo esibalulekileyo ekulweni nezifo ezahlukeneyo ezibangelwa ziintsholongwane ezineGram-positive, ukusuka kusulelo lolusu ukuya kusulelo lokuphefumla. Ukongeza, iThiostrepton ikwabonakalise ukuba iyasebenza ngokuchasene nosulelo oluthile lwefungus. Umsebenzi wayo obanzi uyivumela ukuba ijolise kwiintlobo ngeentlobo zeentsholongwane zentsholongwane, nto leyo eyenza ukuba ibe yi-antibiotic esebenzisekayo.