Ukubonakaliswa kwezinye iikhemikhali ze-insecticidal, ezifana ne-mosquito repellents, zihambelana nemiphumo emibi yempilo, ngokutsho kuhlalutyo lwedatha yokufunda ye-federal.
Phakathi kwabathathi-nxaxheba kwi-National Health and Nutrition Examination Survey (NHANES), amanqanaba aphezulu okuvezwa kwi-pesticides ye-pyrethroid yasekhaya esetyenziswa ngokuqhelekileyo yayanyaniswa nengozi ephindwe kathathu yokufa kwesifo senhliziyo (ingozi ye-3.00, i-95% CI 1.02-8.80) uDkt Wei Bao kunye noogxa kwiYunivesithi yase-Iowa e-Iowa City ingxelo.
Abantu abakwi-tertile ephezulu yokuvezwa kwezi zinambuzane nabo banomngcipheko we-56% wokufa kuzo zonke izizathu xa kuthelekiswa nabantu abakwi-tertile ephantsi yokuvezwa kwezi zinambuzane (RR 1.56, 95% CI 1.08-2. 26).
Nangona kunjalo, ababhali baqaphele ukuba i-pyrethroid insecticides ayizange idibaniswe nokufa komhlaza (RR 0.91, 95% CI 0.31-2.72).
Iimodeli zahlengahlengiswa ngokobuhlanga / ubuhlanga, isondo, ubudala, i-BMI, i-creatinine, ukutya, indlela yokuphila, kunye nezinto zentlalo yoluntu.
Izitshabalalisi zePyrethroid zivunyiwe ukuba zisetyenziswe yi-Arhente yoKhuseleko lweNdalo yase-US kwaye zidla ngokusetyenziswa kwiindawo zokugxotha iingcongconi, izigxothi zeentwala zentloko, iishampu zezilwanyana ezifuywayo kunye nezifafazi, kunye nezinye iimveliso zolawulo lwezinambuzane zangaphakathi nangaphandle kwaye zibonwa njengezikhuselekileyo.
“Nangona ngaphezu kwe-1,000 pyrethroids zivelisiwe, kukho malunga neshumi elinesibini kuphela amayeza okubulala izitshabalalisi kwimarike yaseMelika, njengepermethrin, cypermethrin, deltamethrin kunye necyfluthrin,” iqela likaBao lacacisa, lisongeza ukuba ukusetyenziswa kwepyrethroids “kwandile.”“Kumashumi eminyaka akutshanje, imeko iye yaba mandundu kakhulu ngenxa yokuyekwa ngokuthe ngcembe kokusetyenziswa kwe-organophosphates kwiindawo zokuhlala.“
Kumagqabaza alandelayo, uStephen Stellman, Ph.D., MPH, noJean Mager Stellman, Ph.D., weYunivesithi yaseColumbia eNew York, baphawula ukuba iipyrethroids “zisisibulala-zinambuzane esikwindawo yesibini ehlabathini, ezifikelela kumawaka ezigidi zezilwanyana. iikhilogram kunye namashumi ezigidi zeedola zaseMelika."Ukuthengiswa kwe-US ngeedola zaseMelika.“
Ngaphezu koko, “izibulali-zinambuzane ezibizwa ngokuba yipyrethroid zikho kuyo yonke indawo yaye ukuba sesichengeni akunakuphepheka,” babhala batsho.Asiyongxaki kubasebenzi basezifama kuphela: “Ukutshiza ingcongconi esemoyeni ukulawula intsholongwane ye-West Nile kunye nezinye izifo ezithwalwa zizilwanyana eNew York nakwezinye iindawo kuxhomekeke kakhulu kwipyrethroids,” utshilo uStelmans.
Uphononongo luhlolisise iziphumo ezingaphezu kwe-2,000 yabantu abadala abathathi-nxaxheba kwiprojekthi ye-NHANES ye-1999-2000 abaye bahlolwa ngomzimba, baqokelela iisampuli zegazi, kwaye baphendula imibuzo yophando.I-Pyrethroid exposure yalinganiswa ngamanqanaba omchamo we-3-phenoxybenzoic acid, i-pyrethroid metabolite, kwaye abathathi-nxaxheba bahlulahlulwe kwii-tertiles of exposure.
Ngethuba lokulandelwa kwe-14 iminyaka, abathathi-nxaxheba be-246 bafa: i-52 evela kumhlaza kunye ne-41 kwisifo senhliziyo.
Ngokomyinge, abantu abamnyama abangewona ama-Hispanic bavezwa ngakumbi kwi-pyrethroids kune-Hispanics kunye nabamhlophe abangewona ama-Hispanic.Abantu abanomvuzo ophantsi, amanqanaba emfundo asezantsi, kunye nomgangatho wokutya osezantsi nabo bathande ukuba neyona ndawo iphezulu yokuvezwa kwipyrethroids.
UStellman noStellman baqaqambise "isiqingatha sobomi obufutshane kakhulu" be-pyrethroid biomarkers, umndilili weeyure ezi-5.7 kuphela.
"Ubukho bamanqanaba abonakalayo ee-metabolites zepyrethroid ezipheliswe ngokukhawuleza kwiindawo ezinkulu, ezihlukeneyo ngokweendawo zibonisa ukubonakaliswa kwexesha elide kwaye kwenza ukuba kubaluleke kakhulu ukuchonga imithombo ethile yokusingqongileyo," baphawula.
Nangona kunjalo, baphinde baqaphela ukuba ngenxa yokuba abathathi-nxaxheba bebancinci kwiminyaka yobudala (i-20 ukuya kwi-59 iminyaka), kunzima ukuqikelela ngokupheleleyo ubukhulu bombutho wokufa kwe-cardiovascular mortality.
Nangona kunjalo, "ingozi ephezulu ngokungaqhelekanga" iqinisekisa uphando oluninzi kwezi khemikhali kunye nobungozi obunokubakho kwimpilo yoluntu, uStellman noStellman bathi.
Olunye umda wokufunda, ngokutsho kwababhali, kukusetyenziswa kweesampulu zomchamo wentsimi ukulinganisa i-pyrethroid metabolites, enokuthi ingabonakali utshintsho ekuhambeni kwexesha, okukhokelela ekungacaciswani kakuhle kokuvezwa kwesiqhelo kwi-pyrethroid pesticides.
UKristen Monaco ngumbhali ophezulu ogxile kwi-endocrinology, psychiatry kunye neendaba ze-nephrology.Uzinze kwi-ofisi yaseNew York kwaye ebekunye nenkampani ukusukela ngo-2015.
Uphando luxhaswe yiNational Institutes of Health (NIH) ngeYunivesithi yase-Iowa yeZiko loPhando lwezeMpilo yeNdalo.
Ixesha lokuposa: Sep-26-2023